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Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology. Leveraging human induced pluripotent stem (iPS) cell technology, a team led by Associat

Most cancer deaths are caused not by the initial tumor but by the spread of cancer cells to distant organs in the process called metastasis. Since it occurs at the cellular level, the earliest stages of metastasis are difficult to observe in patients. A new study, published in Sc

New research from an expert in cancer biology explains what triggers liposarcoma cells to become more or less aggressive and identifies potential targets that could keep aggressive tumors in check. A study led by Blake Wilde, Ph.D., of Roswell Park Comprehensive Cancer Center hig

Low arginine levels may allow cancer cells and viruses to slip past the immune system by reducing production of a crucial cellular warning protein. In mice, arginine-rich diets led to fewer colon tumors and milder viral infections, suggesting a simple supplement could have powerf

Stanford researchers discovered immune cells in flatworms that explode within minutes, killing nearby bacteria and foreign cells before vanishing completely. Their unusually fast and localized attack could offer clues for developing targeted treatments against infections and canc

Using simple artificial cells, a research group led by Makito Miyazaki of the RIKEN Center for Integrative Medical Sciences (IMS) in Japan has uncovered fundamental physical principles that govern how living cells change their shape. By combining experiments with computer simulat

Researchers at Karolinska Institutet and SciLifeLab have developed a new method to analyze the condition of immune cells in the blood. The method has been tested on patients with atherosclerosis and can distinguish their immune cells from those of healthy individuals. The study i

New research reveals that cells of the same chronological age can follow dramatically different biological aging paths, offering new insights into cancer, neurodegeneration and the fundamental biology of aging. Rather than aging uniformly, tissues become a mosaic of biologically

The benefits of all three come down to a crucial piece of cellular kitSleep. Exercise. Eat well. It’s the oldest recommendation in medicine, repeated so often it’s become a cliche. We know the advice, even if we don’t always follow it. But have you ever stopped to wonder why thes

A new nanostructured carbon design lets fuel-cell catalysts use tiny amounts of platinum while remaining remarkably stable and efficient. The breakthrough could help hydrogen fuel cells become a more practical way to power data centers, vehicles, and other energy-intensive techno

Stress may literally scramble the brain’s internal GPS. Researchers found that cortisol, a hormone released during stress, made people significantly worse at navigating a virtual environment and disrupted the precise activity of grid cells, specialized brain cells that help us un

Inherited bone marrow failure syndrome, or IBMFS, describes a group of disorders in which inherited genetic abnormalities impair the bone marrow's ability to produce sufficient healthy blood cells. Patients with these disorders are also at increased risk of developing myelodyspla