Sugar molecule could help protect against dangerous hospital fungus Candida auris
Researchers have developed a potential new approach against the highly drug-resistant hospital fungus Candida auris.
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Immune 'reprogramming' could protect poultry from deadly diseases without antibiotics
University of Bristol–led researchers have identified a naturally occurring gut molecule that could strengthen chickens' immune response against a wide range of bacterial infections. This development, published today, Aug. 12, in The Journal of Immunology, offers a major step for
Porous material can arrange disordered gas molecules into a crystal-like structure, study predicts
Capturing carbon or storing hydrogen to combat global warming requires compressing gases into sponge-like porous materials.
DNA origami nanosyringe actively transports molecules into synthetic cells
Transporting molecules across biological membranes is essential for life.
Engineered enzymes forge carbon-carbon and carbon-nitrogen bonds with high selectivity
Researchers from the Manchester Institute of Biotechnology, including Dr. Zachary Birch-Price and professor Anthony Green, have developed a new family of engineered enzymes that can create several different types of chemical bonds used to build complex molecules. This work demons
New GLP-1 pill delivers up to 12% weight loss in 36 weeks
An experimental GLP-1 pill helped people with obesity or overweight lose as much as 12.1% of their body weight in just 36 weeks. Unlike injectable drugs such as Wegovy and Ozempic, aleniglipron is a small molecule that can be taken once daily with or without food and could potent
New molecule class creates hardy, drought tolerant plants
As climate change causes water scarcity and temperatures to rise, crops around the world are feeling the heat. How can we prevent severe crop losses in these relentlessly sweltering conditions? An international research team led by Tohoku University has identified a new class of
First-in-class small molecule inhibitor shows promise against pancreatic cancer in preclin
Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the "undruggable" PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic cancer, grow and resist treatment. In laboratory stud
Charge-based strategy improves controlled delivery of therapeutic peptides from gelatin-ba
Rice University engineers have developed a new strategy for controlling how therapeutic peptides are released from gelatin-based materials, a step that could make the small but powerful molecules more useful in tissue engineering and drug delivery.
Chemists set electrons free and break a decades-old chemistry barrier
Chemists have developed a catalyst that breaks a long-standing rule governing which molecules receive electrons during chemical reactions. By releasing electrons directly into solution, the technique could unlock reactions—and potentially useful new molecules—that were previously